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Classic Quiz

Quiz MD4001 MSA drugs

Classic Quiz

Quiz MD4001 MSA drugs

Elpip

3 played - 13 yrs ago

Pharamacology revision

QUIZ 25 QUESTIONS

expert

Question 1 / 25

Carbamazepine

Acts on CNS to stimulate aminergic transmission (dopamine - euphoria, noradrenaline - locomotor, serotonin - anorexia)

Mechanism unknown

Uses dependent block of Na+ channels

Inhibits cAMP/cGMP phosphodiesterases blocking purine receptors

Question 2 / 25

Felbamate

Unkown

Inhibits GABA transaminase

Acts on CNS to stimulate aminergic transmission (dopamine - euphoria, noradrenaline - locomotor, serotonin - anorexia)

Influences/alters 5-HT (serotonin) transmission of the CNS

Question 3 / 25

Mescaline

Influences/alters 5-HT (serotonin) transmission of the CNS

Uses dependent block of Na+ channels

Blocks GABAa receptors in brain (not spinal cord)

Uses dependent block of Na+ channels

Question 4 / 25

Ecstasy

Mechanism unknown

Influences/alters 5-HT (serotonin) transmission of the CNS

Inhibits cAMP/cGMP phosphodiesterases

Short acting respiratory stimulant

Question 5 / 25

Methylxanthines

Inhibit cAMP/cGMP phosphodiesterases

Influence/alter 5-HT (serotonin) transmission of the CNS

Act on CNS to stimulate aminergic transmission (dopamine - euphoria, noradrenaline - locomotor, serotonin - anorexia)

Block GABAa receptors in brain (not spinal cord)

Question 6 / 25

Nikethamide

Influences/alters 5-HT (serotonin) transmission of the CNS

Acts on CNS to stimulate aminergic transmission (dopamine - euphoria, noradrenaline - locomotor, serotonin - anorexia)

Unkown

Inhibits cAMP/cGMP phosphodiesterases blocking purine receptors

Question 7 / 25

Amphetamine

Short acting respiratory stimulant

Mechanism unknown

Acts on CNS to stimulate aminergic transmission (dopamine, noradrenaline, serotonin)

Blocks GABAa receptors in brain (not spinal cord)

Question 8 / 25

Fenfluramine

Blocks GABAa receptors in brain (not spinal cord)

GABA-uptake inhibitor

Uses dependent block of Na+ channels

Acts on CNS to stimulate aminergic trasmission (dopamine, noradrenaline, serotonin). May have selective action on 5-HT - causes anorexia without stimu

Question 9 / 25

Valproate

Inhibits GABA transaminase

Not clear. Increase in GABA content of the brain. Weak inhibitor of GABA transaminase. Some effect of sodium channels

Uses dependent block of Na+ channels

Influences/alters 5-HT (serotonin) transmission of the CNS

Question 10 / 25

Vigabatrin

Mechanism unknown (simple analogue of GABA)

Inhibits cAMP/cGMP phosphodiesterases blocking purine receptors

Inhibits GABA transaminase

GABA-uptake inhibitor

Question 11 / 25

Ethosuximide

Blocks T-type calcium channels

Mechanism unknown (analogue of piracetam)

GABA-uptake inhibitor

Inhibits NA uptake 1 into adrenergic nerve terminals

Question 12 / 25

Diazepam

Uses dependent block of Na+ channels

Selective 5-HT uptake inhibitor

Blocks delta-receptor and glutamate NMDA-receptor channel. And other neurotransmitter systems

Benzodiazepine - Enhances GABAergic transmission - GABA1 agonist

Question 13 / 25

Doxapram

Blocks GABAa receptor evoked chloride ion entry. (like GABA receptor agonist but not because acts on a site different to the GABA binding site to modu

Influences/alters 5-HT (serotonin) transmission of the CNS

Short acting respiratory stimulant

Blocks glycine receptors - main inhibitory transmitter acting on motorneurons. Works on spinal cord. Causes violent extensor spasms, triggered by mino

Question 14 / 25

Buspirone

5-HT1A receptor agonist

Inhibits GABA transaminase

Blocks Na+ channels

Blocking T-type calcium channels

Question 15 / 25

Cocaine

Influences/alters 5-HT (serotonin) transmission of the CNS

Inhibits NA uptake 1 into adrenergic nerve terminals

Inhibits cAMP/cGMP phosphodiesterases

Acts on CNS to stimulate aminergic transmission (dopamine, noradrenaline, serotonin). May have selective action on 5-HT -causes anorexia without stimu

Question 16 / 25

Gabapentin

Uses dependent block of Na+ channels

Mechanism unknown (simple analogue of GABA)

GABA-uptake inhibitor

Influences/alters 5-HT (serotonin) transmission of the CNS

Question 17 / 25

Levetiracetam

Blocks glycine receptors - main inhibitory transmitter acting on motorneurons. Works on spinal cord. Causes violent extensor spasms, triggered by mino

Blocks GABAa receptors in brain (not spinal cord)

Mechanism unknown (analogue of piracetam)

GABA-uptake inhibitor

Question 18 / 25

Topiramate

Blocks Na+ channels

Blocks GABAa receptor evoked chloride ion entry. (like GABA receptor agonist but not because acts on a site different to the GABA binding site to modu

Mechanism unknown (analogue of piracetam)

Blocks glycine receptors - main inhibitory transmitter acting on motorneurons. Works on spinal cord. Causes violent extensor spasms, triggered by mino

Question 19 / 25

Picrotoxin

Blocks GABAa receptors in brain (not spinal cord)

GABA-uptake inhibitor

Blocks GABAa receptor evoked chloride ion entry. (like GABA receptor agonist but not because acts on a site different to the GABA binding site to modu

Blocks Na+ channels

Question 20 / 25

Strychnine

Blocks glycine receptors - main inhibitory transmitter acting on motorneurons. Works on spinal cord. Causes violent extensor spasms, triggered by mino

Blocks Na+ channels

Unkown

Mechanism unknown (analogue of piracetam)

Question 21 / 25

Lamotrigine

Mechanism unknown (analogue of piracetam)

GABA-uptake inhibitor

Blocks Na+ channels

Blocks GABAa receptors in brain (not spinal cord)

Question 22 / 25

Tiagabine

GABA-uptake inhibitor

Blocks Na+ channels

Blocks GABAa receptors in brain (not spinal cord)

Blocks GABAa receptors in brain (not sActs on CNS to stimulate aminergic transmission (dopamine, noradrenaline, serotonin). May have selectipinal cord

Question 23 / 25

Zonisamide

Unkown

Acts on CNS to stimulate aminergic transmission (dopamine, noradrenaline, serotonin). May have selective action on 5-HT -causes anorexia without stimu

Blocks Na+ channels

Use dependent block of Na+ channels

Question 24 / 25

Bicuculline

Uses dependent block of Na+ channels

Blocks GABAa receptors in brain (not spinal cord)

Unkown

Acts on CNS to stimulate aminergic transmission (dopamine, noradrenaline, serotonin). May have selective action on 5-HT -causes anorexia without stimu

Question 25 / 25

Leptazol

Mechanism unknown (analogue of piracetam)

Unkown

Acts on CNS to stimulate aminergic trasmission (dopmaine, noradrenaline, serotonin). May have selective action on 5-HT - causes anorexia without stimu

GABA-uptake inhibitor

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319 played - 7 mths ago

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350 played - 1 yr ago

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