Classic Quiz
Quiz General knowledge

Quiz Cardiology : Tropomyosin

Tommymoran

Tommymoran
5 played - 12 yrs ago

A proteinate quiz

Hard
hard
26
QUESTIONS
 
Question 1 / 26

Troponin I is...

 
Question 2 / 26

A cross bridge is...

 
Question 3 / 26

The conformation shift in the adjacent troponin complex due to a tropomyosin shift from calcium binding is termed...

 
Question 4 / 26

What is the chance that cross-bridging will induce the formation of another forming...

 
Question 5 / 26

What is the limiting factor in a functioning heart...

 
Question 6 / 26

What is the "blocked-state? "

 
Question 7 / 26

Progression to the closed-state after Ca+ binding to troponin-C is...

 
Question 8 / 26

The closed-state (weakly bound state)'s interaction is analogous to...

 
Question 9 / 26

In a disease heart, the contraction may fail because...

 
Question 10 / 26

ATP propels the myosin head forward from the strong-state (10-15nm), and may...

 
Question 11 / 26

The inefficiency of contracting from the weak state is...

 
Question 12 / 26

In regulating myofilament, what increases cycling rate?

 
Question 13 / 26

What conformational change specifically allows for cycling to increase?

 
Question 14 / 26

What is the lifetime risk of heart failure?

 
Question 15 / 26

What is systolic heart failure?

 
Question 16 / 26

Increasing HR to compensate for poor contractility is...

 
Question 17 / 26

Calcium sensitizers...

 
Question 18 / 26

Pimobendan is...

 
Question 19 / 26

Omecativ Mecarbil is a myosin activator that...

 
Question 20 / 26

Fractional shortening...

 
Question 21 / 26

What is the largest protein in humans?

 
Question 22 / 26

What is the function of titin?

 
Question 23 / 26

PKA and PKG phosphorylate titin to...

 
Question 24 / 26

PKC may be involved in a diseased state because...

 
Question 25 / 26

B-adrenergic receptor can't be targeted in-face of stiffened titin because it is often down-regulated in heart failure. What is a viable downstream target of PKA or PKG?

 
Question 26 / 26

What drug helps to increase titin phosphorylation, and decrease titin stiffness, in experiments on dogs?

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